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Micro Filtration for Fermentation broth

Fermented broth is passed through the microfiltration system results in the separation of bio solids from the soluble phase (MF permeate).  The product of interest can be permeate or retentate. In case of permeate as a product of interest,  it is fed to the downstream spiral membrane separation systems for further separation / concentration of the secondary metabolites.  The MF system ensures that the feed to the downstream spiral membrane system is free of bio solids and allows the downstream system to run smoothly with minimal flux loss and cleaning requirements.

Ultrapure Water

Ultrapure water is a water that has been purified for  stringent specifications. Ultrapure water is a term commonly used in manufacturing to emphasize the fact that the water is treated to the highest levels of purity for all contaminant types, including organic and inorganic compounds; dissolved and particulate matter; volatile and non-volatile; reactive, and inert; hydrophilic and hydrophobic; and dissolved gases. It is widely used as a raw material, ingredient, and solvent in the processing, formulation, and manufacture of pharmaceutical products, active pharmaceutical ingredients (APIs) and intermediates, and analytical reagents. The ultrapure water process begins with pretreatment, typically through ultrafiltration,  2 pass reverse osmosis water filter, UV purification, before employing a deionizing water system of ion exchange or electro-deionization (EDI).